Second illustrated edition, the first with Costaeus's commentary, of the collection of works by the Arab doctor Mesue the Younger (also known as Masawaih al-Mardini) in Latin, with comments by Mondino de Liuzzi, Christoph de Honestis, Jacobus Sylvius, Giovanni Mardi and Johannes Costaeus .. The work includes the "Canones universalis" which deal with treatment regimes; the second part, "De simplicibus", on the properties of various drugs; and Grabadin, "the most popular compendium of drugs in medieval Europe, and used everywhere in their preparation.